Turning survival into the life-years and quality-adjusted life-years a decision is made on, usually far beyond the trial's follow-up. The extrapolation is the part that moves the answer, so it is the part that has to be defensible.
Also called hta, partitioned survival, cost-effectiveness.
Fit it1
pendragonOpen source, in R and Stata. Each page states what has shipped and what is in build.
Try it now2
Partitioned survival analysis explorer Reconstruct & extrapolate a KM curveRuns in your browser. Nothing installed, nothing uploaded.
Worked through2
The evidence5
- Evaluating the Impact of Different Natural History Modeling Methods on Cost-Effectiveness Decisions: A Case Study in Duchenne Muscular Dystrophy.
- A Framework for the Estimation of Quality-Adjusted Life-Years Using Joint Models of Longitudinal and Survival Data.
- Developing a Natural History Model for Duchenne Muscular Dystrophy.
- Multivariate Generalized Linear Mixed-Effects Models for the Analysis of Clinical Trial–Based Cost-Effectiveness Data.
- What is the clinical and cost-effectiveness of using drugs in treating obese patients in primary care? A systematic review.